myopathy ddx

• Keywords:: Step 3, Allergy and Immunology

Myopathy occurs in approximately one-third of patients with hypothyroidism and can range from an asymptomatic elevation in CK to myalgias, muscle hypertrophy, proximal myopathy, and rhabdomyolysis. Serum CK can be elevated for years before a patient develops clinical symptoms of hypothyroidism, and there is no clear correlation between the degree of CK elevation and severity of muscle disease. Inflammatory markers (eg, erythrocyte sedimentation rate, C-reactive protein) may be normal or mildly elevated. Initial testing should include TSH and free T4 levels.

fibromyalgia vs polymyositis vs polymyalgia rheumatica

Muscle Weakness

Spinal Myelopathy